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By their nature, polymers and polyelectrolytes tend to be very sensitive to changes in their environment. QCM-D is employed to:

  • Monitor the hydration/solvation of polymer films in both liquid or gaseous environments
  • Follow the crosslinking of polymeric films
  • Characterize the incorporation and binding of proteins (and other molecules) to the polymer film
  • Complex edifices, such as polyelectrolyte multilayers, can be characterized at any time during their build-up process. Multi-frequency measurements and adapted modeling provide quantification of the film’s thickness and viscoelastic properties

The “feel for the solvent” renders the QCM-D technique particularly adapted for thin films (nanometers to micrometers) that are highly solvated.

Please find application notes on your right.

Watch Q-Sense animation of multilayer formation, swelling or Q-Sense animation in full.

References can also be found in the publication database.


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07 Real time thickness monitoring of polyelectrolyte multilayer formation
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10-2 Studying nucleation kinetics of bioceramics
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11 Swelling kinetics of a cellulose model film
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23 Polyelectrolyte multilayer and crosslinking